Biotin repressor stress
WebJan 1, 2001 · Cooperative association of the Escherichia coli biotin repressor with the biotin operator is allosterically activated by binding of the corepressor, bio-5'-AMP. The corepressor function of... WebNov 14, 2024 · In this study, we establish OmpR as a global regulator of acid and osmotic stress in S. Typhimurium and E. coli. OmpR represses distinct sets of genes based on the intracellular pH threshold...
Biotin repressor stress
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WebMay 15, 1998 · The Escherichia coli repressor of biotin biosynthesis, BirA, binds to a 40 bp operator site (bioO) to repress transcriptional initiation at the two divergent promoters of the biotin biosynthetic operon (Figure 1A; Otsuka & Abelson, 1978). WebSep 25, 2001 · Diphtheria toxin repressor protein (DtxR) is a 226-amino acid residue, iron-dependent transcriptional regulator of genes in Corynebacterium diphtheriae that code for diphtheria toxin and proteins involved in iron uptake and oxidative stress (1, 2).DtxR is the best characterized member of a family of related proteins from primarily Gram-positive …
WebNov 4, 2005 · The co-repressor buttresses the dimer interface, resulting in improved packing and a 12 degrees change in the hinge-bending angle along the dimer interface relative to the BirA.biotin structure. This helps explain why the binding of the co-repressor is necessary to optimize the binding of BirA to the bioO operator. WebNational Center for Biotechnology Information
WebMay 15, 2001 · The biotin repressor, BirA, is a critical protein in regulation of biotin retention and biosynthesis in Escherichia coli.Biotin is retained in the cell as a coenzyme that is covalently linked to biotin-dependent carboxylases ().In E. coli this two-step reaction is catalyzed by BirA. The adenylate of biotin is first synthesized from substrates biotin … WebNov 11, 1991 · Proteins most abundant in S-phase cells were stress associated and transporters plus transferases in agreement with the general phenomenon that binding protein-dependent systems are induced under nutrient limitation as part of hunger response. ... The Escherichia coli biotin repressor is a member of the “winged helix-turn-helix” …
WebOct 1, 1992 · The three-dimensional structure of BirA, the repressor of the Escherichia …
WebMay 24, 2016 · The paradigm version of BPL is the Escherichia coli BirA that is also a repressor for the biotin biosynthesis pathway. Streptococcus suis, a leading bacterial agent for swine diseases, seems to... the wild river 1994WebFeb 1, 2003 · The biotin repressor is an allosterically regulated, site-specific DNA-binding protein. Binding of the small ligand bio-5'-AMP activates repressor dimerization, which is a prerequisite to DNA binding. the wild riceWebNov 9, 2002 · The Escherichia coli biotin repressor, an allosteric transcriptional … the wild riverWebBiotin is a member of the vitamin B-complex family. Biotin deficiency has been … the wild ride imdbWebNov 14, 2024 · Acid stress reduces the internal pH below this threshold, increasing OmpR dimerization and DNA binding. ... in the ompR null mutant, suggesting that E. coli OmpR also functions as a repressor at ... the wild reindeer read aloudWebJan 31, 2003 · The biotin repressor is an allosterically regulated, site-specific DNA-binding protein. Binding of the small ligand bio-5′-AMP activates repressor dimerization, which is a prerequisite to DNA binding. Multiple disorder-to-order transitions, some of which are known to be important for the functional allosteric response, occur in the vicinity ... the wild rings isoWebNov 15, 2013 · Many biological switches including the stress response [1] and biofilm formation [2] in bacteria and inflammation [3] and development [4] in higher organisms are controlled at the level of protein:protein interactions. In each of these systems, the switch involves swapping of one protein interaction partner for another. the wild ride 1960