Ctp biosynthetic process
WebDec 13, 2024 · Enables CTP synthase activity. Involved in CTP biosynthetic process and larval lymph gland hemopoiesis. Acts upstream of with a positive effect on phospholipid metabolic process. Located in cytoophidium and cytoplasm. Is expressed in several structures, including extended germ band embryo; germ layer; ovary; presumptive … WebPyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2. UniRule annotation. Features. Showing features for binding site, active site. Type. ID ... Biological Process 'de novo' CTP biosynthetic process Source:UniProtKB-UniPathway. Biological Process: glutamine metabolic process Source:UniProtKB-KW. Expand table.
Ctp biosynthetic process
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WebOct 31, 2013 · Pyrimidine nucleotide biosynthetic process 19 4 10.728 −3.352 CTP biosynthetic process 9 3 16.986 −3.241 Pyrimidine ribonucleoside triphosphate metabolic process 9 3 16.986 −3.241 Pyrimidine ribonucleoside triphosphate biosynthetic process 9 3 16.986 −3.241 CTP metabolic process 9 3 16.986 −3.241 . WebFunction. Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ( PubMed: 5793714 ). Required for repair of UV radiation- and etoposide-induced DNA damage ( PubMed: 18983998 ).
WebInvolved in CTP biosynthetic process; phospholipid biosynthetic process; and pyrimidine nucleobase biosynthetic process. Located in cytoophidium. Human ortholog(s) of this …
CTP (cytidine triphosphate) synthetase catalyzes the last committed step in pyrimidine nucleotide biosynthesis: ATP + UTP + glutamine → ADP + Pi + CTP + glutamate It is the rate-limiting enzyme for the synthesis of cytosine nucleotides from both the de novo and uridine salvage pathways. The reaction proceeds by the … See more CTP synthase is an enzyme (EC 6.3.4.2) involved in pyrimidine biosynthesis that interconverts UTP and CTP. See more Active CTP synthase exists as a homotetrameric enzyme. At low enzyme concentrations and in the absence of ATP and UTP, CTP synthase exists as inactive monomer. As enzyme concentration increases, it polymerizes first to a dimer (such as the form … See more CTP synthase has been reported to form filaments in several different organisms. These include bacteria (C. crescentus), yeast ( See more • Pyrimidine biosynthesis See more Two isozymes with CTP synthase activity exist in humans, encoded by the following genes: • See more CTP synthase is precisely regulated by the intracellular concentrations of CTP and UTP, and both hCTPS1 and hCTPS2 have been seen to be maximally active at physiological concentrations of ATP, GTP, and glutamine. The activity of … See more Upregulated CTP synthase activity has been widely seen in human and rodent tumors. Mutations in the … See more WebCytidine triphosphate (CTP) is an allosteric inhibitor representing a classic case of feedback inhibition whereby the end product of a biosynthetic pathway inhibits an enzyme …
WebJul 25, 2006 · Biological Process: CTP biosynthetic process Source:UniProtKB. Biological Process: glutamine metabolic process Source:UniProtKB-KW. Biological Process: pyrimidine nucleobase biosynthetic process Source:GO_Central. 1 publication. Biological Process: T cell proliferation Source:UniProtKB. Expand table. Complete GO annotation …
WebSynechococcus elongatus PCC 7942 Gene-Ontology-Terms Class: GO:0006241 - CTP biosynthetic process Synonyms: CTP anabolism, CTP biosynthesis, CTP formation, … d-project株式会社WebWe tial, universally conserved enzyme responsible for catalyzing the rate-limiting test our method on available structures of a rabbit muscle aldolase, two 20S step in CTP biosynthesis – conversion of UTP to CTP in an ATP-dependent proteasome complexes, and a bacterial 70S ribosome complex. Resolutions process. dproject 茨城WebCtp synthase activity. Specific Function. This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. This enzyme and its product, CTP, play a crucial role in the proliferation of activated ... d projectsWebCTP synthase 1: RGD ID: 1311060: Description: Predicted to enable CTP synthase activity and identical protein binding activity. Predicted to be involved in lymphocyte proliferation and pyrimidine-containing compound biosynthetic process. Predicted to be active in cytoophidium and cytoplasm. Human ortholog(s) of this gene implicated in ... radio broadcast magazineWebCTPS is a glutamine amidotransferase enzyme that catalyzes the conversion of uridine triphosphate (UTP) to CTP and is a key enzyme in nucleic acid and phospholipid … d project management skillsWebctp synthase activity: ligase activity, forming carbon-nitrogen bonds: Molecular Function; ATP binding: CTP synthase activity: Process; metabolic process: nitrogen compound … d project tracksuitWebMar 21, 2024 · CTPS1 (CTP Synthase 1) is a Protein Coding gene. Diseases associated with CTPS1 include Immunodeficiency 24 and Nemaline Myopathy 7.Among its related pathways are Pyrimidine metabolism and UTP and CTP dephosphorylation II.Gene Ontology (GO) annotations related to this gene include hydrolase activity and CTP … d project suzuka