WebMay 28, 2004 · Several isoforms of fibroblast growth factor-2 (FGF2) are expressed: the low molecular weight 18-kDa protein (FGF2lmw) is secreted and activates tyrosine … WebThe role of the 18-kDa isoform of fibroblast growth factor-2 (FGF2) in the maintenance of bone mass was examined in Col3.6-18-kDa FGF2-IRES-GFPsaph transgenic (18-kDa …
Jianzhou CHEN University of Oxford, Oxford OX Research profile
WebFindings demonstrate a potent antifibrotic effect of FGF2lmw administration, which may provide a novel approach to treat chronic liver diseases and have distinct roles in liver fibrogenesis. Liver fibrosis, a major cause of end‐stage liver diseases, is closely regulated by multiple growth factors and cytokines. The correlation of fibroblast growth factor 2 … WebDownload scientific diagram Immunofluorescence localization of FGF-2 isoforms. Cells were plated at 8,000 cells/chamber in eight-chamber slide and grown for 24 h in 10% FBS medium. Indirect ... flannel boy shorts
Tumour-associated macrophages express FGF receptors.
WebIn the Fgf2lmw-ko/lmw-ko mice, the HMW isoforms were only expressed in the nucleus. In the Fgf2hmw-ko/hmw-ko mice, the LMW isoform was localized in the cytoplasm and nucleus of the heart. The nuclear localization of the FGF2 LMW isoform may indicate NIH-PA Author Manuscript that the FGF2 LMW isoform can elicit its biological activity not only ... WebDownload scientific diagram Deletion analysis of the bFGF promoter and mapping of the cAMP and PMA-responsive regions. BAMC were transfected using DNA lipofection or electroporation. (A ... WebApr 29, 2014 · Transgenic mice with targeted overexpression of FGF2lmw and FGF2hmw in immature and mature osteoblast lineage (via Col3.6-cre) are used to elucidate the differential functions of FGF2 isoforms in ... can salt water cause hair loss