WebJun 14, 2012 · Hepatic fibrosis is an important complication after Fontan surgery in patients with single-ventricle congenital heart disease. Few reports of hepatic histology in these patients exist, and sinusoidal fibrosis has been described. We aimed to characterize fibrosis at liver biopsy procedure in patients with previous Fontan surgery and to identify … WebAbstract. Objectives: Liver disease is an important contributor to morbidity and mortality in patients after Fontan surgery. There has been no large-scale survey of liver health in this population. We sought to explore the prevalence and predictors of liver disease in a multicenter cohort of adults with Fontan physiology.
Fontan Liver Disease: Review of an Emerging Epidemic and
WebThe authors of a recent white paper have called for liver biopsy after 10 years after Fontan and further follow-up and treatment based on the extent of fibrosis. 37 As a means of standardizing the results of pathology, Sirius red staining, which captures portal and sinusoidal fibrosis, or the Congestive Hepatic Fibrosis Score, which captures ... WebAug 18, 2024 · The Fontan operation has dramatically altered the natural history of functionally single ventricle congenital heart disease. Patients who have undergone the Fontan operation are living longer and, thus, noncardiac morbidity resulting from the Fontan operation is increasingly being recognized. Fontan-associated liver disease (FALD), one … swanton invest
Liver function monitoring in Fontan-procedure patients: audit of ...
WebJun 2, 2024 · Assessment of liver function in the Fontan patient group, be it with non-invasive laboratory investigations, liver biopsy, or imaging techniques, is important for the early identification of serious pathology, such as liver cirrhosis, fibrosis or … WebNov 16, 2024 · Palliative Fontan surgery offers enhanced survival 1 and quality of life for patients with univentricular heart. Despite reported long-term survival, 1 progressive failure of the Fontan circulation is expected, characterized by ventricular dysfunction and systemic complications, such as Fontan-associated liver disease (FALD). Heart transplantation … Webrelated to the unique Fontan physiology. Fontan-associated liver disease (FALD) is a process universal to the post-Fontan population and includes a spectrum of pathology that ranges from mild liver fibrosis (LF) to liver cirrhosis (LC) and hepatocel-lular carcinoma (HCC). 1,2 We will review advances in the field skippack bocce courts