Aberrant cell cycle regulation is a classical hallmark of cancer and a promising target for therapeutic intervention (Hanahan & Weinberg, 2011). Since the D-Cyclins were regarded as redundant and mere activators of CDK4/6 in B-ALL, our findings provide not only an intriguing insight into fundamental B-cell … See more B-cell acute lymphoblastic leukemia (B-ALL) is the most common cancer among children with a second peak in incidence later in life. It is associated with good … See more What makes CCND3 so special? Since B-ALL is a heterogeneous malignancy comprising multiple different genotypes, underlying driver mutations, and genetic … See more Web10 Jan 2024 · Franz Ketzer, Thomas Wirth & Alexey Ushmorov Institute of Immunology, Ulm University Medical Center, Albert-Einstein-Allee 11, 89081, Ulm, Germany Hend …
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WebRT @Hema_News: Led by Franz Ketzer (@ketzer_franz), scientists conclude that CCND3 plays an essential role in the maintenance of B cell #AcuteLymphoblasticLeukemia 喝, … WebFacebook oyfest baltimore
Dr. Franz Ketzer on LinkedIn: Postgrad Position at the Center of ...
WebCongratulations to the Ushmorov group and especially to Franz Ketzer as the first author. They published the article “CCND3 is indispensable for the maintenance of B-cell acute lymphoblastic leukemia” in the Nature Journal Oncogenesis.They identified the direct transcriptional regulation of CCND3 by FOXO1 and demonstrated why CCND3 depletion … Web8 Mar 2024 · Franz Ketzer, Hend Abdelrasoul, … Alexey Ushmorov Transcriptional CDK inhibitors, CYC065 and THZ1 promote Bim-dependent apoptosis in primary and recurrent GBM through cell cycle arrest and Mcl-1 ... WebDr. Franz Ketzer received his BSc in Nutritional Sciences at Friedrich-Schiller-University Jena, Germany in 2016. He conducted his thesis on the effect of aluminum-nanoparticles on colon cancer cells supervised by Prof. Dr. Michael Glei, sparking his interest in cancer research. In 2024, he proceeded to complete the MSc curriculum in Molecular ... oyf 226 motherboard