Webb2 aug. 2016 · Wu and colleagues developed a diagnostic scoring system for elements of the patient’s history. Risk factors identified include age younger than 3 years, failed or delayed passage of meconium, and male sex. Scaled scores indicating Hirschsprung disease predict the disease with a sensitivity of 83%, specificity of 90%, and accuracy … WebbHirschsprung's disease is a condition characterized by the absence of ganglion cells in a variable segment of the large intestine, mainly producing the symptom of constipation …
Rectal biopsy for Hirschsprung
Webb12 jan. 2024 · The gold standard for the diagnosis of Hirschsprung’s disease (HD) is a rectal biopsy. The sample may be obtained using a transanal excisional biopsy (TEB) or suction technique. Rectal suction biopsy (RSB) is not a standard procedure in Latin–America. To evaluate the current practice in rectal biopsy for HD among pediatric … Webb6 dec. 2024 · Hirschsprung disease (HD) is a congenital disease that is characterized by the lack of enteric neuron formation during the embryonic period, with the absence of ganglion cells and hypertrophy of nerve trunks in the … thika nursing school
Diagnosis of Hirschsprung Disease Request PDF - ResearchGate
Webb9 apr. 2024 · Using our experience from a case of foetal volvulus due to a congenital mesenteric defect with a delay in diagnosis which led to the baby's death, we carried out a literature review about the pathogenesis, clinical presentation and prognosis, in order to identify the gold standard management for this fragile group of babies and reduce the … Webb6 dec. 2024 · Background Hematoxylin-eosin (HE) staining of a full-thickness rectal wall fragment is classically used for the diagnosis of Hirschsprung disease (HD). However, this technique requires large fragments for a better diagnosis. Additionally, the histochemical and immunohistochemical methods of staining small fragments of rectal … WebbThe gold standard for definitive diagnosis of Hirschsprung disease is histologic evaluation of rectal biopsy, where the absence of ganglion cells in the submucosal and myenteric plexuses is the definitive finding. The biopsy should be taken at least 1-1.5 cm above the dentate line because there is a normal paucity of ganglion cells below this ... thika power limited